We can find four
major organic compounds in organisms.
That major organic compounds have basic chemical nature and functions. We will
study them one by one.
The major organic compounds that found in organisms are,
• Carbohydrates
• Lipids
• Proteins
• Nucleic acids
These
major organic compounds considered as major biological molecules.
Carbohydrates
• Most abundant organic matter on earth
• The substances that we know as sugars and
flour in day-to-day life are examples
• Major elemental composition is C,H,O
• General formula Cx(H2O)y
- Hydrates of carbon contains the same proportions of
H:O (2:1) found in water
• Monosaccharides, disaccharides and
polysaccharides are the three main classes
of carbohydrates
Monosaccharides
• Name
monosaccharides according to the number
of C atoms as; Triose
(3C
) e.g. Glyceraldehyde, Tetrose (4C) e.g. Erythrose - rare in nature,
Pentose (5C) e.g.Ribose, Ribulose, Hexose(6C) e.g. glucose, fructose, galactose.
• All Monosaccharides are reducing sugars
Disaccharides
• Maltose, Lactose are reducing sugars, Sucrose
is not a reducing sugar.
Polysaccharides
• Polysaccharides
structured as, 1-4 glycosidic bonds and 1-6
glycosidic
bonds. Straight chains and branched chain structure. Basic
structure and
functions of starch, glycogen and cellulose.
Amylase
activity on starch. Inulin as an example of another polysaccharide and
hemicellulose, pectin and chitin as important polysaccharide derivatives
Lipids
• Heterogeneous group of compounds which are insoluble in water.
• Major elemental composition is C,H,O sometimes P and/or N. Less oxygen
than carbohydrates
• The structure of fatty acids - saturated and unsaturated with examples.
• Distinguish oils and fats. Triglyceride structure of oils and fats.
• Give examples of other trypes of fats e.g., waxes, phospholipids, steroids
And terpenes.
• Explain major functions of lipids.
• Laboratory tests to identify fats and oils.
Proteins
• State proteins are linear polymers of amino acids with high molecular
weights. They contain C,H,O, N and sometimes S.
• State amino acids as monomer units of proteins. Although there are
Several amino acids in the body only around 20 different amino acids are
involved in making proteins. Explain what are peptide bonds , how they are
formed and Polypeptide structure.
• Complex structure of proteins can be described in 4 stages.
• Primary - Sequence of amino acids.
• Secondary - helical or pleated sheet structure
• Tertiary - bending, folding of polypeptide chains produce globular shape.
Different types of bonds stabilizing tertiary structure.
• Quartenery- aggregation of 2 or more polypeptides to form a complex
structure
Nucleic acids
• Linear polymers of high molecular weight, contains C, H, O, N and P.
• Two types - DNA and RNA.
• Nucleotides as building units. Constituents of nucleotides.
• Types of N-bases. Purines and pyrimidines. Difference of sugars and
Bases of nucleotides of DNA and RNA
• Polynucleotide structure. Explain fully the double helical structure of DNA.
• Self replication of DNA
• Denaturation of DNA. Renaturation of DNA.
• Differences between RNA and DNA. Three different types of RNA (mRNA,
t-RNA and r-RNA).
• Functions of DNA and RNA
• Nucleotides other than those found in nucleic acids and their functions.
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